2018年3月，前俄羅斯間謀Sergei Skripai及其女兒在英國被人下毒，毒藥被證實為蘇聯在冷戰時期所研發的神經毒素Novichok。1058Please respect copyright.ＰＥＮＡＮＡl2VNC9P5Hq
1058Please respect copyright.ＰＥＮＡＮＡX9crmmpmGT
2020年8月20日，一名極力反對普京的社會領袖Alexei Navalny，亦遭受到同類型的毒素傷害，表面證據暫時相信為被人在茶裡下毒。1058Please respect copyright.ＰＥＮＡＮＡjBGQdNX9Ad
1058Please respect copyright.ＰＥＮＡＮＡTG9tT4HmZN
本篇深入淺出，將會簡述神經系統的運作，以及神經毒素Novichok的機制。1058Please respect copyright.ＰＥＮＡＮＡ5lz54jFdem
1058Please respect copyright.ＰＥＮＡＮＡNXiEatcWU9
1058Please respect copyright.ＰＥＮＡＮＡuKAtZFGHIY
1058Please respect copyright.ＰＥＮＡＮＡKm6Qc6FPRe
（圖1）神經線負責傳遞信息，為身體內的橋樑。橋樑並不是緊密相扣著的，一條神經線質另一條神經線互相均有著一道空隙。1058Please respect copyright.ＰＥＮＡＮＡikgKrIMt02
1058Please respect copyright.ＰＥＮＡＮＡ9gIaqGD3xj
1058Please respect copyright.ＰＥＮＡＮＡcjOREex83e
1058Please respect copyright.ＰＥＮＡＮＡkRnPbLkvty
1058Please respect copyright.ＰＥＮＡＮＡedqSGgBMHn
（圖2）訊息在神經線中主要是以電流的方式傳遞。1058Please respect copyright.ＰＥＮＡＮＡaOrRpoE2Pg
1058Please respect copyright.ＰＥＮＡＮＡpSHovFb0ja
電流來到神經線A的末端後，便會觸發ACh釋出，使ACh來到神經線之間的空隙。1058Please respect copyright.ＰＥＮＡＮＡDRioVoFwZ2
1058Please respect copyright.ＰＥＮＡＮＡPngnd2VUQu
ACh與另一神經線的Receptor結合後，便會觸發新一道的電流產生，使訊息一直能傳遞到終點。1058Please respect copyright.ＰＥＮＡＮＡMR9ut3rKFd
1058Please respect copyright.ＰＥＮＡＮＡFZRNrMigTo
1058Please respect copyright.ＰＥＮＡＮＡxIjcRhDI4W
1058Please respect copyright.ＰＥＮＡＮＡuXghTN77ez
1058Please respect copyright.ＰＥＮＡＮＡuqNP2hfuPw
（圖3）神經線空隙的AChE負責分解ACh，以免電流長期持續產生。1058Please respect copyright.ＰＥＮＡＮＡ95LYpEO3P2
1058Please respect copyright.ＰＥＮＡＮＡrQPiEEibhs
而俄國最愛的神經毒素Novichok則會與AChE合併及抑制AChE的功能，導致ACh不會被分解，使ACh無了期與神經線的Receptor結合，長期產生神經線電流的傳播，導致患者出現抽搐、癲癇等症狀，沒能適時治療的話更會導致死亡。1058Please respect copyright.ＰＥＮＡＮＡRmtS4FjcER
1058Please respect copyright.ＰＥＮＡＮＡ1dCAMltur9
解毒劑暫時有幾種，Atropine能阻截ACh與Receptor合併，Pralidoxime能夠促使Novichok無法與AChE結合。1058Please respect copyright.ＰＥＮＡＮＡPdgJiRjPT1
1058Please respect copyright.ＰＥＮＡＮＡXR2YRJd4H1
這些解毒劑雖然可以使患者康復起來，但患者的認知及肌肉功大有可能會有收到永久性的損害。1058Please respect copyright.ＰＥＮＡＮＡozf3ZO8Kr1
1058Please respect copyright.ＰＥＮＡＮＡkMWfLXewck
如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。1058Please respect copyright.ＰＥＮＡＮＡ7Y7MI6gD2E
1058Please respect copyright.ＰＥＮＡＮＡCt3uH4Geb3
Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc1058Please respect copyright.ＰＥＮＡＮＡGp94PkvKSf
1058Please respect copyright.ＰＥＮＡＮＡGWbyfT5x5t
同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」，以課金的方式推動我繼續搜羅資料寫文，多謝。1058Please respect copyright.ＰＥＮＡＮＡdUTo9fL7va
1058Please respect copyright.ＰＥＮＡＮＡHzdHXo0FtP
Link:1058Please respect copyright.ＰＥＮＡＮＡU6yOMHnpKO
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio1058Please respect copyright.ＰＥＮＡＮＡIHZ46baGCE
1058Please respect copyright.ＰＥＮＡＮＡHKVdRGqW4L
1058Please respect copyright.ＰＥＮＡＮＡbj69URk4Pm
有興趣接收科普資訊的話，歡迎follow IG: potatopigtongue。1058Please respect copyright.ＰＥＮＡＮＡckjwjzpf7V
8964 copyright protection1054ＰＥＮＡＮＡPC7r9cQMlz 維尼

216.73.216.70