科普專欄–薯不揀單 - 深入淺出–治理暗瘡的新方向

暗瘡對大部份人來說可謂是一道萬惡的存在，尤其是愛靚唔愛命的女士們的公敵。683Please respect copyright.ＰＥＮＡＮＡCa5D6o1e95
683Please respect copyright.ＰＥＮＡＮＡVKbnL21Kab
在講述暗瘡的形成之前，我們首先需要了解一下皮膚的背景資料。683Please respect copyright.ＰＥＮＡＮＡ4m5g1cPjrY
683Please respect copyright.ＰＥＮＡＮＡwQpATzENR8
683Please respect copyright.ＰＥＮＡＮＡmqBTjmoK4i
（圖1）皮膚是人類最大的器官，它是我們一道抵禦外來物入侵的防線，同時亦提供了一個優良環境給予各式各樣的細菌及真菌成長及聚居。683Please respect copyright.ＰＥＮＡＮＡXXDZVFWSlp
683Please respect copyright.ＰＥＮＡＮＡqt7IAv2SIg
除皮膚表層外，那些細菌及真菌亦可聚居在髮囊、負責散熱的汗腺及負責分泌油脂的皮脂腺裡頭。683Please respect copyright.ＰＥＮＡＮＡgy3Tq3ielJ
683Please respect copyright.ＰＥＮＡＮＡf3aYbUIXqx
683Please respect copyright.ＰＥＮＡＮＡ33udlDTzQt
683Please respect copyright.ＰＥＮＡＮＡjwFtvY5Xtm
（圖2）皮膚最外層的細胞全都是已死的細胞(Dead Cells)，學名為Enucleated keratinocytes。683Please respect copyright.ＰＥＮＡＮＡPZGqmZy7DZ
683Please respect copyright.ＰＥＮＡＮＡLtSRzb4GqN
這些已死的細胞會不斷脫落，大概每日總共會脫落50億這些已死的細胞，而下層已死的細胞會逐漸補上，日復如是。683Please respect copyright.ＰＥＮＡＮＡaZi9cKEWfD
683Please respect copyright.ＰＥＮＡＮＡnjruGgprTJ
683Please respect copyright.ＰＥＮＡＮＡwIEXbUkNQs
683Please respect copyright.ＰＥＮＡＮＡzrPOTQSctu
（圖3）暗瘡的形成，與那些表層細胞有著莫大的關係。683Please respect copyright.ＰＥＮＡＮＡe7zeQfAnYL
683Please respect copyright.ＰＥＮＡＮＡvTL8bR11LM
以下為形式暗瘡的簡略三步曲：683Please respect copyright.ＰＥＮＡＮＡTecLwu8wSh
683Please respect copyright.ＰＥＮＡＮＡLdgPGevbBf
1.皮膚表面已死細胞脫落到髮囊裡頭。683Please respect copyright.ＰＥＮＡＮＡU1uN5aNsWm
683Please respect copyright.ＰＥＮＡＮＡYUbYvTdabw
2.皮脂腺釋出油脂，因已死細胞阻窒通道，導致油脂無法離開，久而久之便成為黑頭。683Please respect copyright.ＰＥＮＡＮＡK4BMdHVC7D
683Please respect copyright.ＰＥＮＡＮＡbIOe92lDOg
3.聚居在油脂腺的細菌分解油脂為更簡單結構的油脂物，而這些油脂物觸動發炎反應，造就暗瘡的誕生。683Please respect copyright.ＰＥＮＡＮＡtU5mINqjYF
683Please respect copyright.ＰＥＮＡＮＡDdkUPl5fnU
683Please respect copyright.ＰＥＮＡＮＡy9kY9CiHcQ
683Please respect copyright.ＰＥＮＡＮＡr9YoGOtSQX
（圖4）青春期荷爾蒙作怪，油脂分泌特別旺盛，所以年青人特別容易生暗瘡。683Please respect copyright.ＰＥＮＡＮＡZEqKgUw10c
683Please respect copyright.ＰＥＮＡＮＡ2kCzMdA2zq
但是，有些人就算做足日常護理都會特別容易生暗瘡，而有些不愛日常臉部護理的懶鬼就死都唔會生暗瘡，裡頭究竟是甚麼原因呢？683Please respect copyright.ＰＥＮＡＮＡrATanBabWa
683Please respect copyright.ＰＥＮＡＮＡXc4m5N03ON
683Please respect copyright.ＰＥＮＡＮＡ8JoYEK2IH9
683Please respect copyright.ＰＥＮＡＮＡheKh6fX3xx
（圖5）大量的研究指出，Cutibacterium acnes (C. acnes)是人體皮膚最常見且數量眾多的一種細菌，亦是暗瘡促成的元兇。683Please respect copyright.ＰＥＮＡＮＡ4aEnjxe7Gx
683Please respect copyright.ＰＥＮＡＮＡhL6akXwBzT
易生暗瘡以及不易生暗瘡的人，C. acnes 數量並沒有太大的分別，但品種上有著一道顯著的分別。683Please respect copyright.ＰＥＮＡＮＡ3zvf9ayONq
683Please respect copyright.ＰＥＮＡＮＡIxLOSSiLI7
易生暗瘡人皮膚上的C. acnes 品種更有效率代謝皮脂腺所釋出的油脂，亦即是更容易促成發炎反應形成暗瘡。683Please respect copyright.ＰＥＮＡＮＡZRPGOo9mZx
683Please respect copyright.ＰＥＮＡＮＡCQXeFxFVMz
683Please respect copyright.ＰＥＮＡＮＡsbrktw5kB0
683Please respect copyright.ＰＥＮＡＮＡm0sAaJgI5h
（圖6）現時治理暗瘡的手法大多會用上benzoyl peroxide或retinoic acid，目的是刺激皮膚及減低油脂的分泌。683Please respect copyright.ＰＥＮＡＮＡnmEkhhJo36
隨著科技的進步及對皮膚細菌的認識，科學界有著思想上的轉變，認為改變皮膚上的細菌群組才是對付暗瘡治標且治本的方法。683Please respect copyright.ＰＥＮＡＮＡtuxFX0hict
683Please respect copyright.ＰＥＮＡＮＡq0UaniMQCD
現時只至有三種治理暗瘡的嶄新手段正進行臨床階段之中。683Please respect copyright.ＰＥＮＡＮＡYYHvpv1YBr
683Please respect copyright.ＰＥＮＡＮＡTrm3mmKld6
1.把不易生暗瘡的人皮膚表面上的C. acnes放到易生暗瘡人士上，企圖以良幣消除劣幣的方式取代舊有的C. acnes。683Please respect copyright.ＰＥＮＡＮＡJmozjlCS1c
683Please respect copyright.ＰＥＮＡＮＡXj9oFbH4MG
2.把失去化謝油脂能力的C. acnes取代舊有的C. acnes。683Please respect copyright.ＰＥＮＡＮＡzXvMsEBVeD
683Please respect copyright.ＰＥＮＡＮＡim8ocrnaEV
3.把懂得釋放抑制發炎化應化學物的C. acnes取代舊有的C. acnes。683Please respect copyright.ＰＥＮＡＮＡjNUGUYHypS
683Please respect copyright.ＰＥＮＡＮＡwSNBXZbgeH
今年的十月相信會有這些臨床研究的進一步結果的分析，但願這種治療方式會為暗瘡人士帶來一股新希望。683Please respect copyright.ＰＥＮＡＮＡXtrfXyDPxa
683Please respect copyright.ＰＥＮＡＮＡqB0ISEkJch
683Please respect copyright.ＰＥＮＡＮＡYVPl6s8vHK
如果想我快啲出文的話，請入去Penana網站科普專欄–薯不揀單俾一個like以及Bookmark，這對我非常之重要。683Please respect copyright.ＰＥＮＡＮＡ2eLSYgXMJp
683Please respect copyright.ＰＥＮＡＮＡ50YmdScEuN
Link: https://www.penana.com/story/66244/%E7%A7%91%E6%99%AE%E5%B0%88%E6%AC%84-%E8%96%AF%E4%B8%8D%E6%8F%80%E5%96%AE/toc683Please respect copyright.ＰＥＮＡＮＡxkumUolf87
683Please respect copyright.ＰＥＮＡＮＡc9wFupTQNn
同時亦可以在Penana網站裡按「買一嚿/半嚿薯仔」，以課金的方式推動我繼續搜羅資料寫文，多謝。683Please respect copyright.ＰＥＮＡＮＡP3YD8geJq2
683Please respect copyright.ＰＥＮＡＮＡ9B03iUolWr
Link:683Please respect copyright.ＰＥＮＡＮＡRkQeG2L0EJ
https://www.penana.com/user/27349/%E8%96%AF%E4%BB%94%E8%81%9E%E8%8C%B1%E8%8E%89/portfolio683Please respect copyright.ＰＥＮＡＮＡsRF2gctkzI
683Please respect copyright.ＰＥＮＡＮＡP2u58OrA96
683Please respect copyright.ＰＥＮＡＮＡZseN4q1ejC
有興趣接收科學資訊的話，歡迎follow IG: potatopigtongue。